Premenstrual Disorder Linked to Lower Quality of Life and Tense Relationships

A study spearheaded by Dr. Sophie Hodgetts within our Psychology Department has revealed the concealed effects of Premenstrual Dysphoric Disorder (PMDD) on overall well-being and interpersonal connections.
PMDD is a serious cyclic hormonal mood disorder affecting between 2% and 5% of individuals who have menstrual cycles globally.
The research examined the impact on individuals suffering from the condition and their partners, an effect that was previously not well understood. The document is published in the journal PLOS ONE .
Standard of living and interpersonal connections
The research encompassing over 400 people found that those experiencing PMDD stated they had a diminished quality of life as well as poorer relationship experiences.
The research revealed numerous obstacles encompassing different facets of daily living such as physical health, mental well-being, social interactions, and environmental conditions.
Individuals with PMDD, who made up more than half of the participants (216 people), reported feeling a reduced level of intimacy, trust, and passion in their relationships.
Impacts on partners
The observations were also supported by the partners of those affected, highlighting significant effects on their overall well-being and interpersonal connections.
The research contrasted the reactions of 92 partners of individuals with PMDD, versus 59 partners of those whose significant others experience regular menstruation without having PMDD.
The partners of people with PMDD reported experiencing significant stress, a reduced sense of personal development and value, challenges or an inability to fulfill their caregiver responsibilities effectively, and an overall sensation of being un-supported.
They similarly noted comparable degrees of discontent within their partnerships as those who live with the condition. Nonetheless, both individuals dealing with the issue and their significant others concurred that "love" and "commitment" were not impacted.
What is PMDD?
PMDD is frequently confused with PMS (Premenstrual Syndrome); however, these two conditions differ significantly in terms of intensity and effect.
Although premenstrual syndrome (PMS) may result in slight emotional shifts, agitation, and bodily unease prior to menstruation, premenstrual dysphoric disorder (PMDD) extends well past those symptoms, causing extreme emotional disruptions, profound anxiety, depressive episodes, violent anger, and at times, contemplation of suicide.
These symptoms appear during the luteal phase, which is from one to two weeks prior to menstruation, and usually subside soon after the menstrual cycle starts.
Future research
These results indicate that additional and upcoming clinical studies should focus on creating targeted therapies for PMDD that assist not only the individual suffering from it but also their partner.
Dr. Hodgetts's ongoing research with IAPMD seeks to explore further the dimensions of relationships impacted by PMDD.
Upcoming research initiatives entail conducting interviews and focus group discussions with individuals who have PMDD as well as their family members and close associates. This approach aims at pinpointing key areas where interventions can be made and developing effective support methods.
Furthermore, the partnership is examining the personal experiences of individuals receiving treatment for PMDD and delving into how PMDD intersects with neurodiversity.
More information: Sophie Hodgetts and colleagues investigated how premenstrual dysphoric disorder (PMDD) affects overall life satisfaction and relationship quality through an online cross-sectional survey study. PLOS ONE (2025). DOI: 10.1371/journal.pone.0322314
Provided by Durham University
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